abstract：:BACKGROUND Intestinal complications are a major cause of morbidity after colorectal cancer surgery. This study aimed to develop an effective nomogram for predicting risk of intestinal complications following colorectal cancer surgery. MATERIAL AND METHODS We retrospectively analyzed 1876 patients who underwent colorec...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang HH,Dong XL,Tang X,Li AJ,Chang Y,Li HG,Chen Y,Zhang ZY,Tang EJ,Lin MB

更新日期：2019-03-21 00:00:00

abstract：:BACKGROUND The aim of this study was to assess the presence of HPV DNA in cervical tissues and lymph nodes in patients who have uterine cervical neoplasms with lymphatic metastases and who underwent surgery for invasive cervical cancer and pelvic lymphadenectomy, to establish the utility of HPV type and viral load in ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen P,Zhang W,Yang D,Zhang W,Gao S

更新日期：2019-03-13 00:00:00

abstract：:BACKGROUND Pulsed radiofrequency of genicular nerves in the management of osteoarthritis related chronic knee pain has recently become a promising treatment. Ultrasonography has replaced fluoroscopic guidance in pain medicine. The aim of this study was to investigate the effect of ultrasound-guided genicular pulsed ra...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Erdem Y,Sir E

更新日期：2019-03-12 00:00:00

abstract：:BACKGROUND This study investigated the cardioprotective effect of isosorbide dinitrate (ISDN) postconditioning against rat myocardial ischemia/reperfusion injury in vivo and provided a theoretical basis for clinical application. MATERIAL AND METHODS We randomly divided 32 Wistar rats into 4 groups: sham group, I/R (is...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao X,Wang M,Li M,Wu N,Song D

更新日期：2019-03-02 00:00:00

abstract：:BACKGROUND This article presents our experience in managing a rare kidney tumor - reninoma - by analyzing a relatively large series of cases from a single center. MATERIAL AND METHODS Nine cases of reninoma were reviewed. Clinical manifestations, imaging examinations, laboratory examinations, perioperative data, and p...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu K,Wang B,Ma X,Li H,Zhang Y,Li J,Yao Y,Tang L,Xuan Y,Guo A,Zhang X

更新日期：2019-03-01 00:00:00

abstract：:BACKGROUND Gelsolin (GSN) is an actin-binding and PIP₂/Ca²⁺-regulated protein found in the cytoplasm and blood plasma. Hypogelsolinemia occurs in a wide range of traumatic injuries and inflammatory reactions. We hypothesize that blood GSN levels will be altered in patients diagnosed with acute myeloid leukemia (AML) t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wątek M,Wnorowska U,Wollny T,Durnaś B,Wolak P,Kościołek-Zgódka S,Pasiarski M,Góźdź S,Bucki R

更新日期：2019-02-23 00:00:00

abstract：:BACKGROUND In traditional Chinese medicine, acupuncture has been used to treat angina due to coronary artery disease (CAD). The aim of this systematic review of the literature and meta-analysis was to identify published randomized controlled trials (RCTs) that quantified the effectiveness of adjunctive acupuncture tre...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang X,Guo S,Li F,Tan X,Cai Q,Wang H,Chen P,Wang G,Ma X

更新日期：2019-02-16 00:00:00

abstract：:BACKGROUND The purpose of this study was to explore the immune mechanism of dendritic cells (DCs) against measles virus (MV), and to identify potential biomarkers to improve measles prevention and treatment. MATERIAL AND METHODS The gene expression profile of GSE980, which comprised 10 DC samples from human blood infe...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jia L,Zhang R

更新日期：2019-02-01 00:00:00

abstract：:BACKGROUND Diabetes is a risk factor for coronary atherosclerosis and coronary heart disease. Resveratrol (RESV) is a natural compound with anti-inflammatory effects. The objective of this study is to evaluate the cardio protective effects of RESV in a diabetic rat model with coronary heart disease. MATERIAL AND METHO...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huo X,Zhang T,Meng Q,Li C,You B

更新日期：2019-01-18 00:00:00

abstract：:BACKGROUND This study aimed to investigate the effects of metastasis-associated 1 (MTA1) gene expression and gene silencing in human non-small cell lung cancer (NSCLC) cells in vitro and on angiogenesis in tumor xenografts in vivo in nude mice. MATERIAL AND METHODS Human H460 and H1299 NSCLC cell lines underwent trans...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang T,Li W,Huang H,Wang C

更新日期：2019-01-17 00:00:00

abstract：:BACKGROUND Osteoporosis is a common disorder leading to bone loss. At present, the treatment options available for the management of osteoporosis are limited. The present investigation evaluated the protective effect of fangchinoline against osteoporosis and also postulates the possible mechanism of action. MATERIAL A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu W,Ding W,Shang X,Zhu D,Dai X

更新日期：2019-01-11 00:00:00

abstract：:BACKGROUND Effective early management of cerebral infarction patients with transient ischemic attack (TIA) is undermined by an inability to predict who is at highest risk of stroke. MATERIAL AND METHODS A total of 577 TIA patients with symptoms lasting no more than 1 hour were prospectively investigated and divided in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lu Y,Yu J,Hu J,Tan Y,Wu J,Zhao Y,Liu X

更新日期：2019-01-02 00:00:00

abstract：:BACKGROUND Aminoglycosides, a type of gram-negative antibacterial, are broad-spectrum antibiotics that are highly potent and have satisfactory therapeutic efficacy in the treatment of life-threatening infections. Our study aimed to establish a gentamicin-induced cochlear injury model and to investigate the cochlear ne...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang F,Gong S,Zhou Y,Huang C,Li T,Li Q,Ceng X,Wang C

更新日期：2018-12-28 00:00:00

abstract：:BACKGROUND Abdominal bleeding is a severe complication of duodenal fistula, but few studies have focused on this problem. The purpose of the present study was to investigate the prevalence of and risk factors for intra-abdominal bleeding in patients with external duodenal fistula. MATERIAL AND METHODS From January 201...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yao Z,Ge Z,Xu X,Pu P,Ren X,Zhao Y,Qin C

更新日期：2018-12-21 00:00:00

abstract：:BACKGROUND Lymphocyte-to-monocyte ratio (LMR) is an independent predictive factor of clinical outcome of acute ischemic stroke and cancer, but the predictive effect of LMR in spontaneous intracerebral hemorrhage (ICH) is unknown. Thus, the aim of this study was to explore the impact of peripheral LMR on the neurologic...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qi H,Wang D,Deng X,Pang X

更新日期：2018-12-20 00:00:00

abstract：:BACKGROUND Endometriosis is a common gynecologic disorder with enigmatic etiopathogenesis and is characterized by tumor-like biological behaviors. Recently, circular RNAs (circRNAs) have attracted considerable attention because they exert very important functions in the progression of human cancers. However, little is...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang M,Ren C,Xiao Y,Xia X,Fang X

更新日期：2018-12-19 00:00:00

abstract：:BACKGROUND Colorectal carcinoma (CRC) is one of the most frequently diagnosed malignancies. Cucurbitacin B (CuB) is a natural compound isolated from herbs and shows anticancer activity in several cancers. MATERIAL AND METHODS Here, we analyzed the effects of different CuB concentrations on the proliferative and invasive...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chai Y,Xiang K,Wu Y,Zhang T,Liu Y,Liu X,Zhen W,Si Y

更新日期：2018-12-19 00:00:00

abstract：:BACKGROUND Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA, which has also been identified in somatic tissues, and aberrant expression of piRNAs in tumor tissues may be implicated in carcinogenesis. piR-823 is increased in liver cirrhosis and hepatocellular carcinoma (HCC). However, there is n...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tang X,Xie X,Wang X,Wang Y,Jiang X,Jiang H

更新日期：2018-12-17 00:00:00

abstract：:BACKGROUND The myosin heavy chain 10 or MYH10 gene encodes non-muscle myosin II B (NM IIB), and is involved in tumor cell migration, invasion, extracellular matrix (ECM) production, and epithelial-mesenchymal transition (EMT). This study aimed to investigate the effects of the MYH10 gene on normal human glial cells an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang Y,Yang Q,Cheng Y,Gao M,Kuang L,Wang C

更新日期：2018-12-15 00:00:00

abstract：:BACKGROUND The purpose of this study was to explore the function and mechanism of peroxisome proliferator activated receptor agonist (PPARγ) in the toll-like receptor 2 (TLR2)/nod-like receptor with pyrin domain containing 3 (NLRP3) inflammatory corpuscle pathway of asthmatic mice. MATERIAL AND METHODS Eighteen female...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cheng Y,Li S,Wang M,Cheng C,Liu R

更新日期：2018-12-13 00:00:00

abstract：:BACKGROUND The aim of this study was to compare the alterations in intraocular pressure (IOP) values during the early postoperative period after intravitreal ranibizumab, aflibercept, or dexamethasone implant injections. MATERIAL AND METHODS In this retrospective study, a total of 188 patients were grouped into 3 grou...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Karakurt Y,Ucak T,Taslı G,Agcayazı B,İcel E,Yılmaz H

更新日期：2018-12-13 00:00:00

abstract：:BACKGROUND A urine albumin to creatinine ratio (UACR) >30 mg/g is considered to represent albuminuria, but in type 2 diabetes mellitus, even low-grade albuminuria is associated with increased risk of cardiovascular disease. This study aimed to investigate the effects of metformin and acarbose treatment on urine albumi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pan Q,Xu Y,Yang N,Gao X,Liu J,Yang W,Wang G

更新日期：2018-12-10 00:00:00

abstract：:BACKGROUND Epithelial ovarian cancer (EOC) has a high mortality rate and is a common malignant tumor of women, seriously impairing health. Chemoresistance is one of the major causes of poor prognosis. Therefore, analyzing the molecular mechanism of paclitaxel resistance has great significance. MATERIAL AND METHODS We ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Shi C,Wang M

更新日期：2018-12-06 00:00:00

abstract：:BACKGROUND This study was conducted to investigate the effects of low frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex on depression and cognition in patients with traumatic brain injury. MATERIAL AND METHODS To accomplish this, 13 patients who were diagnosed wi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lee SA,Kim MK

更新日期：2018-12-04 00:00:00

abstract：:BACKGROUND Hypoxia induces cell apoptosis in the uterosacral ligaments of patients with pelvic organ prolapse by upregulation of hypoxia-inducible factor-1α (HIF-1α). This study aimed to investigate the effects of HIF-1α on human uterosacral ligament fibroblasts (hUSLFs) following treatment with the chemical inducer o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao X,Liu L,Li R,Wei X,Luan W,Liu P,Zhao J

更新日期：2018-12-03 00:00:00

abstract：:Osteoporosis is a common skeletal disease characterized by bone loss and subsequent increased risk of fragility fractures. Recent advances in our mechanistic understanding of molecular communications among osteoblasts, osteoclasts, and osteocytes give insight into the important roles of the canonical Wnt/β-catenin pat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chang B,Quan Q,Li Y,Qiu H,Peng J,Gu Y

更新日期：2018-12-03 00:00:00

abstract：:BACKGROUND Long non-coding RNAs (lncRNAs) have been implicated in various human cancer types. However, the underlying mechanisms involved in hepatocellular carcinoma (HCC) progression remain poorly understood. MATERIAL AND METHODS In this study, lncRNA array was used to identify HCC related lncRNAs. RNA immunoprecipit...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li O,Li Z,Tang Q,Li Y,Yuan S,Shen Y,Zhang Z,Li N,Chu K,Lei G

更新日期：2018-11-25 00:00:00

abstract：:BACKGROUND Dental age is less affected than the bone age by nutritional and hormonal factors. The assessment of dental age in children is of value in clinical and forensic practice. The aims of this study were to compare the Demirjian method and the Willems method in the assessment of dental age in children in Poland ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sobieska E,Fester A,Nieborak M,Zadurska M

更新日期：2018-11-19 00:00:00

abstract：:BACKGROUND The aim of this study was to dynamically evaluate tooth movement, root resorption, and remodeling of alveolar bone using different forces to cause tooth movement in rats. MATERIAL AND METHODS 12-week-old male Sprague-Dawley rats were selected. Nickel-titanium (Ni-Ti) coil springs (20 g, 50 g, and 100 g forc...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou J,Yang F,Xu X,Feng G,Chen J,Song J,Dai H

更新日期：2018-11-18 00:00:00

abstract：:BACKGROUND The distribution of fat mass and obesity-associated gene (FTO) genes rs9939609 and rs1421085 in obese and normal ethnic Mongolians was analyzed to investigate the association of FTO gene polymorphisms with obesity and metabolic syndrome in ethnic Mongolians. MATERIAL AND METHODS The genotypes of FTO genes r...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Q,Xia X,Fang S,Yuan X

更新日期：2018-11-16 00:00:00

abstract：:BACKGROUND Therapeutic evaluation of 3-dimensional conformal radiotherapy (3DCRT) is rarely reported for non-resectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). The aim of this study was to determine the value of contrast-enhanced ultrasound (CEUS) in evaluating the therapeutic response o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li H,Liu J,Chen M,Li H,Long L

更新日期：2018-11-14 00:00:00

abstract：:BACKGROUND Chronic spinal cord injury (CSCI) is a worldwide clinical problem. We aimed to reveal differentially expressed (DE) lncRNAs and to find associated pathways that may function as targets for CSCI therapy. MATERIAL AND METHODS After a CSCI rat model was confirmed by the Basso Beattie Bresnahan (BBB) scale and ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang L,Yang L,Li W,Yang Y,Sun W,Gong P,Wang L,Wang K

更新日期：2018-11-09 00:00:00

abstract：:BACKGROUND Gemcitabine plus cisplatin (GP) is a novel regimen of induction chemotherapy (IC) for treating locoregional advanced nasopharyngeal cancer (NPC). This retrospective study aimed to compare the efficacy of GP and TP (paclitaxel plus cisplatin) regimens in tumor volume reduction after IC. MATERIAL AND METHODS ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng L,Liao W,Xu P,Li B,Wen H,Zhang S

更新日期：2018-11-08 00:00:00

abstract：:BACKGROUND Nasal obstruction is the most common rhinologic complaint in ear, nose, and throat (ENT) clinical practice and septal deviation is the leading cause. The Nasal Obstruction Symptom Evaluation (NOSE) scale is a brief, self-administered questionnaire that has been widely used to assess symptoms and quality of ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dąbrowska-Bień J,Skarżyński H,Gos E,Gwizdalska I,Lazecka KB,Skarżyński PH

更新日期：2018-11-06 00:00:00

abstract：:BACKGROUND This study investigated the expression of Bax/Bcl-2, TGF-β1 and type III collagen fiber in sternocleidomastoid of congenital muscular torticollis (CMT), and explored the possible mechanisms of fibrosis in sternocleidomastoid of CMT. MATERIAL AND METHODS The localization and expression of Bax, Bcl-2, TGF-β1,...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li D,Wang K,Zhang W,Wang J

更新日期：2018-11-03 00:00:00

abstract：:BACKGROUND The downregulation of tropomyosin 1 (TPM1) has been observed in various tumors, but few studies have focused on the clinical significance of TPM1 in intrahepatic cholangiocarcinoma (ICC). In the present study, we investigated the prognostic significance of TPM1 in ICC. MATERIAL AND METHODS A total of 124 pa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Hong Z,Lu S,Zhang N,Rong G,Chang X,Liu Z,Bai W,Dong Z,Gao X,Zeng Z,Lu Y

更新日期：2018-11-03 00:00:00

abstract：:BACKGROUND Phenylketonuria (PKU) is an inborn error of metabolism caused by mutations in the phenylalanine hydroxylase (PAH) gene. When untreated, PKU leads to a significant intellectual deficiency. Although early initiation of dietary therapy allows normal cognitive development, low adherence to treatment may result ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Vieira Neto E,Maia Filho HS,Monteiro CB,Carvalho LM,da Cruz TS,de Barros BV,Ribeiro MG

更新日期：2018-10-30 00:00:00

abstract：:BACKGROUND Liver cancer is the third leading cause of tumor-related deaths worldwide. Stomatin-like protein 2 (STOML2) is obviously upregulated in various tumors. In this study, we explored the potential roles and mechanisms of si-STOML2 in the migration and invasion of human hepatoma LM3 cells. MATERIAL AND METHODS T...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu W,Li W,Geng Q,Wang X,Sun W,Jiang H,Pu X

更新日期：2018-10-25 00:00:00

abstract：:BACKGROUND The aim of this study was to assess the passive stiffness of the medial and lateral gastrocnemius (MG and LG), Achilles tendon (AT), and plantar fascia (PF) at different ankle and knee positions. MATERIAL AND METHODS Stiffness was assessed using a portable hand-held device (MyotonPRO). In 30 healthy partici...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang J,Qin K,Tang C,Zhu Y,Klein CS,Zhang Z,Liu C

更新日期：2018-10-23 00:00:00

abstract：:BACKGROUND Non-small cell lung cancer (NSCLC) accounts for about 85% of all types of lung cancer. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is involved in DNA methylation, and DNA methylation is related to tumorigenesis. The role of MTHFD1 in NSCLC was examined in our study. MATERIAL AND METHODS The correlati...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ding K,Jiang J,Chen L,Xu X

更新日期：2018-10-21 00:00:00